方法：收录90例年龄相关性白内障伴中、高度散光患者(104眼)，施行白内障超声乳化联合AcrySof散光型人工晶体植入术。患者在规定的复查时间接受必要的检查。通过KR-1W视觉质量分析仪检测AcrySof散光型人工晶体的稳定性。观察指标包括裸眼远视力(UDVA)、最佳矫正远视力(CDVA)以及显然验光结果。通过配对T检验及ANOVA检验分析结果。

结果：研究共纳入104眼，从术前检查至最后一次术后复查持续24个月。7次复查时间点观察到AcrySof散光型人工晶体的位置没有显著变化，P=0.863； 所有患者的裸眼远视力(logMAR，4.39±0.27至4.77±0.22； P<0.001)、最佳矫正远视力(logMAR， 4.54±0.25至4.93±0.14； P<0.001)以及显然验光\〖度(D)， -1.27±0.98至-0.97±0.71， P=0.003\〗均有显著改善。术后调制传递函数(MTF)较术前提高。

结论：研究显示AcrySof散光型人工晶体具有很好的旋转稳定性。该种人工晶体可以减少显然验光的柱镜度数、提高视力并改善视力相关的生活质量。

METHODS: A total of 104 eyes of 90 patients with age related cataract and moderate to high regular astigmatism underwent phacoemulsification and implantation of AcrySof toric IOL(SN6AT series; Alcon, Fort Worth, TX, USA). Patients underwent comprehensive examinations at standard intervals. The rotational stability of AcrySof toric intraocular lens was evaluated using visual quality analyser KR-1W(Topcon, Tokyo, Japan). Uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA)and manifest refraction were also recorded. The outcomes were analysed by paired-samples T test and ANOVA Test.

RESULTS: From preoperatively to the last visit(24mo), 104 eyes were included in the clinical trial. The AcrySof toric IOL axis orientation(at seven visits)did not show significant change, P=0.863. All of the eyes had significant improvement in UDVA(logMAR, 4.39±0.27 to 4.77±0.22; P<0.001), CDVA(logMAR, 4.54±0.25 to 4.93±0.14; P<0.001)and manifest refraction astigmatism \〖diopters(D), -1.27±0.98 to -0.97±0.71, P=0.003\〗. There was an increase in MTF results between preoperative and postoperative evaluations.

CONCLUSION: The AcrySof toric IOL shows good rotational stability. It can reduce manifest refraction cylinder and improve visual acuity and vision-related quality of life permanently.