方法：前瞻性设计。对2008-10/2012-04济南军区总医院眼科泪道门诊接诊的先天性泪道阻塞患者，在接受泪道探通的同时妥布霉素地塞米松眼膏注入，并对治疗效果进行了分析。

结果：根据病史，59例儿童(男38例，女21例)中，5例(8.47%)双眼受累，其中1眼于12月龄时自愈，共64眼纳入研究。接受治疗时的年龄为16.9(3～96)mo。1女性患儿因双侧骨性鼻泪管发育不全，未完成探通，除1眼需二次探通外，其余所有患者均一次探通后缓解。接受治疗时的年龄、眼别、慢性炎症不影响最终疗效，未见严重并发症。

结论：与其他治疗方法相比，作为首次治疗或单纯泪道探通失败后的替代疗法，泪道探通联合妥布霉素地塞米松眼膏注入治疗儿童鼻泪管阻塞十分安全有效。

METHODS:Prospectively designed lacrimal probing with simultaneous infusion of TobraDex ointment infusion was conducted for CNLDO children at the Lacrimal Clinic, Jinan Military General Hospital from Oct. 2008 to Feb. 2012. The results were retrospectively reviewed.

RESULTS:According to the medical histories, five out of fifty-nine(8.47%)children(38 boys, 21 girls)were bilaterally affected, with one eye being spontaneously resolved at 12mo of age before treatment. Sixty-four eyes were finally enrolled. The average age at surgery was 16.9mo(range: 3-96mo). There was an incomplete probing of one female with bilateral dysplasia of the bony nasolacrimal duct. All remaining obstructions were resolved after single probing, except for one eye that received a re-probe. Age, side operation, and chronic infection at the time of surgery appeared to have no influence on the final outcome. No significant complications were encountered.

CONCLUSION: Compared with other treatment modalities, probing with a lumbar needle and TobraDex ointment infusion for pediatric nasolacrimal obstruction is highly effective and safe, both as a primary treatment and an alternative measure after failed simple probing.