目的：从主客观方面比较超声乳化术(PKE)和手法小切口白内障手术(SICS)术后致干眼的研究，并对致病因素进行分析。

方法：单中心前瞻性研究。选取2013-07/2014-12接受同一医生治疗白内障手术及人工晶体植入术患者，100例患者100眼分为两组(第一组：50例50眼手法小切口白内障手术患者； 第二组：50例50眼超声乳化术患者)。术后所有干眼患者都作表记录，从主客观方面评估其第1、4、12wk术后干眼情况，并分析其致病诱因。

结果：干眼测试(DET)值在主客观方面无显著差异(P>0.05)。相较于各自术前值，尽管期间无显著变化(P>0.05)，两组在第12wk目标干眼测试值呈持续下降趋势(P<0.05)。超声乳化术在第12wk结束时干眼测试值更主观。

结论：白内障术后干眼症是不可避免的。在术后12wk前超声乳化术组和手法小切口白内障手术组术后干眼测试值影响相似。进一步研究需要更多样本、更长随访时间的随机多中心临床试验来证实。

AIM: To evaluate and compare subjective and objectively, the course of surgically induced dry eye following both phacoemulsification(PKE)and manual-small incision cataract surgery(SICS)procedure, and to analyze the result in terms of causative factors.

METHODS:This single centre prospective study included 100 eyes of 100 patients randomly divided into two groups(Group 1, SICS-50 patients; Group 2, PKE-50 patients), who underwent cataract surgery with intraocular lens(IOL)-implantation from Jun. 2013 to Dec. 2014 for a period of one and half year by single surgeon. In all patients post operative course of dry eye were tabulated and assessed at 1, 4, 12wk, subjectively and objectively, and thereafter analyzed in terms of possible causative factors. Statistical data were calculated using SPSS 23.0 Windows software.

RESULTS:There was no significant preoperative intergroup difference in subjective and objective dry eye test(DET)values(P>0.05). Both the groups showed similar trend of persistently declining objective DET-values till at the end 12wk, as compared to their respective preoperative values(P<0.05), although there were no significant intergroup changes seen throughout the postoperative period(P>0.05). PKE seems to have better subjective DET-value at the end of 12wk.

CONCLUSION:Dry eye disease is inevitable following cataract surgery. Both PKE and SICS, can affect the dry eye test values in almost similar manner post operatively till up to 12wk. Randomized multicentre trial with larger cohort and longer follow-up is warranted to substantiate our findings.