AIM: To compare three kinds of surgical treatment of nasolacrimal duct obstruction secondary to the efficacy and safety of dacryocystitis, and to explore the clinical treatment of nasolacrimal duct obstruction secondary to the best operation for dacryocystitis.

METHODS: A total of 348 cases with nasolacrimal duct obstruction secondary dacryocystitis patients(397 eyes)were selected in Jan.2010 to Jan.2016 of our hospital as the research object. According to the treatment of surgery, the research subjects were divided into three groups respectively. The lacrimal duct laser group(130 patients, 152 eyes), the nasolacrimal duct group(113 patients, 127 eyes)and the nasal endoscopy group(105 patients, 118 eyes)of lacrimal duct laser group patients accepted the treatment of lacrimal duct laser lines. Nasolacrimal duct group patients received artificial nose tube stents implantation treatment, patients with nasal endoscopy group underwent anastomosis of lacrimal sac nasal endoscope. The therapeutic effect in three groups of patients and the incidence of adverse reactions were analyzed.

RESULTS: After 1mo, 3 groups of eye treatment effect were statistically significant difference(P<0.05). Lacrimal duct effect of laser treatment group significantly was better than that of the nasolacrimal duct and nasal endoscopy group(P<0.05). The nasolacrimal duct group compared with the effect of nasal endoscopic treatment group was no statistically significant difference(P>0.05). Postoperative 4mo, 3 groups of eye treatment effect comparison results were completely accorded with postoperative 1mo. But the three groups of 4mo after treatment were significantly difference with postoperative 1mo(P<0.05). The incidence of adverse reactions difference in 3 groups was statistically significant(P<0.05). The incidence of adverse reactions of lacrimal duct laser group was significantly lower than the nasolacrimal duct and nasal endoscopy group(P<0.05). The nasolacrimal duct incidence of adverse reactions compared differences between groups with and nasal endoscopy had no statistically significant(P>0.05). Three groups of eye recurrence rate comparison difference had no statistically significant(P>0.05).

CONCLUSION: For the treatment of lacrimal duct laser lines nasolacrimal duct obstruction secondary efficacy and safety of dacryocystitis were good.