[关键词]
[摘要]
目的：系统评价SMILE和飞秒激光制瓣的LASIK(FS-LASIK)矫正近视后疗效的差异。
方法：检索PubMed、The Cochrane Library、Sciverse、万方和CNKI 数据库，对比较FS-LASIK和SMILE术后疗效的文献进行Meta分析。
结果：共有5篇文献符合本研究的纳入标准，共689例999眼。Meta分析结果显示： SMILE和FS-LASIK 治疗近视在有效性\〖OR=0.83，95%CI(0.52～1.33)\〗、可预测性\〖OR=0.54，95%CI(0.22～1.29)\〗 和安全性\〖OR=1.10，95%CI(0.80～1.51)\〗比较差异均无统计学意义。
结论：SMILE和FS-LASIK矫正近视安全、有效，都有较好的视力矫正效果。但受纳入研究质量低、统计结果不稳定等因素的限制，上述结论尚需更多设计严谨的大样本随机对照试验进一步验证。
[Key word]
[Abstract]
AIM:To review the efficacy of SMILE and femtosecond laser-guided LASIK(FS-LASIK)in correction of myopia.
METHODS:The PubMed, Cochrane Library, SciVerse, WanFang Data and CNKI databases were searched for Meta-analysis of literature comparing FS-LASIK and SMILE outcomes.
RESULTS:A total of 5 literatures met the inclusion criteria of this study, a total of 689 cases(999 eyes). Meta-analysis showed: SMILE and FS-LASEK myopia treatment effectiveness \〖OR=0.83, 95%CI=(0.52, 1.33)\〗, predictability \〖OR=0.54, 95%CI=(0.22, 1.29)\〗 and security \〖OR=1.10, 95%CI(0.80, 1.51)\〗 no statistically significant difference.
CONCLUSION:SMILE and FS-LASIK correction of myopia is safe, effective, have good vision correction effect. However, due to the low quality of the included studies and the instability of the statistical results, the above conclusions need to be further validated by more rigorous randomized controlled trials.
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