Abstract:As the continuous improvement and development of cataract surgery technology and intraocular lens(IOL), patients with postoperative visual quality requirements are no longer confined to "see", but is durable and comfortable to "see". Aberration is the important factors affecting postoperative visual quality. It includes low-order aberrations and higher-order aberrations. Low-order aberration can be corrected easily, but high-order aberration is more difficult to correct, and the higher order, the more difficulty to correct. Studies have showed that high order aberrations increase with age not only including spherical aberration, but also coma. But the change is far less than the spherical aberration, and other higher-order aberrations are close to zero. So spherical aberration becomes key area of high-order aberration attention and research in ophthalmology. Conventional spherical IOL has positive spherical aberration. It can not correct positive corneal spherical aberration of human eyes. In order to correct the positive corneal spherical aberration, the aspherical IOLs which design with zero or negative spherical aberration have been produced, studies have shown that it can obtain better postoperative visual quality than traditional spherical IOL, but how to comprehensively evaluate different spherical aberration aspherical IOL eye vision quality and how to choose it individually are the problems need to solve right now. For the best corrected spherical aberration of IOL eyes is uncertain, studies found that the amount of positive spherical aberration general approach to obtain a better visual quality, and can increase the depth of focus, which can increase far and near vision. In this paper, we will summarize the research progress on individual choice of aspheric IOL, to provide clinical basis about how to choose it individually for clinicians.