AIM: To investigate the clinical efficacy of phacoemulsification and intraocular lens implantation combined with goniosynechialysis for angle-closure glaucoma.

METHODS: A retrospective analysis was performed. A total of 215 patients with angle-closure glaucoma associated with cataract who underwent treatment in department of ophthalmology of our hospital from Jul.1, 2014 to May 30, 2016 were recruited in this study. All patients' preoperative intraocular pressures were ≥21 mmHg. The cataract phacoemulsification and intraocular lens implantation combined with goniosynechialysis were performed. The intraocular pressure(IOP), visual acuity, anterior chamber depth, anterior chamber angle before and after surgical procedures were measured and analyzed. All patients were followed for at least 6mo(mean 13.8±6.9mo; range: 6-25mo).

RESULTS: The mean IOP decreased significantly, falling from 20.4±8.1 mmHg to 13.5±3.3mmHg(P<0.05). During the postoperative follow-up, all patients' IOP lower than 21mmHg. Visual acuity and anterior chamber depth increased significantly as well. No significant reduction in corneal endothelial cell count was observed. In addition, there was no serious complications observed in all patients.

CONCLUSION: Phacoemulsification and intraocular lens implantation combined with goniosynechialysis for angle-closure glaucoma can achieve satisfactory clinical efficacy. It also has high safety.