AIM: To investigate the related factors affecting the prognosis of central serous retinopathy(CSC).

METHODS: A total of 75 patients with CSC were selected in our hospital from Jan.2013 to Jan.2015 as the object of study. The clinical data of patients were retrospectively analyzed, and fundus fluorescence angiography for patients. The cause of the related factors of poor prognosis in patients were analyzed.

RESULTS: A total of 46 cases of patients 92 eyes, 61% with good prognosis, 29 cases(58 eyes)of poor prognosis, accounting for 39%. Comparison of good prognosis and poor prognosis of patients in the number of sex, age, there was no significant difference(P>0.05). In terms of course of disease, the leakage type, from the point of leakage, leakage area comparisons, the difference is statistically significant(P<0.05). Multivariate analysis showed that age, duration of disease, type of leakage, distance of leakage point and leakage area were the risk factors for poor prognosis of CSC(P<0.05). Course of disease, the type of leakage, leakage location, leakage area were positively correlated with the poor prognosis of CSC(r=0.367,0.269, 0.518, 0.325, P<0.05).

CONCLUSION: There are many factors that lead to poor prognosis of CSC, the area, location, type and course of leakage are the risk factors of CSC prognosis.