AIM: To investigate the effect of lacrimal passage laser combined with drainage tube implantation on tear film rupture time and corneal fluorescein sodium staining in patients with lacrimal duct obstruction so as to improve the therapeutic effect of lacrimal laser combined drainage tube implantation.

METHODS: From January, 2013 to December, 2015, 200 cases(200 eyes)of lacrimal passage obstruction were treated with lacrimal passage laser combined with lacrimal drainage tube implantation in our hospital. Before and 1mo after operation, after the tube was draw out, ocular surface was assessed. The test included tear film rupture time, tear secretion, corneal fluorescein staining and dry eye syndrome questionnaire.

RESULTS: There was no significant difference in tear film rupture time between the two groups before and after 1mo, after the tube was draw out(P>0.05). The amount of tear secretion increased at 1mo after operation and the amount of tear secretion decreased after extubation. The difference was statistically significant(P<0.05). There was no significant difference in the corneal fluorescein staining before and after operation, after extubation(P>0.05). The dry eye symptom questionnaire showed that the tearing laser combined drainage tube implantation significantly improved the tearing symptoms.

CONCLUSION: The lacrimal duct laser combined drainage tube implantation has no significant effect on tear film rupture time and corneal fluorescein sodium staining. This kind of operation can improve the postoperative tearing symptoms of the patients, and is of great significance in the treatment of lacrimal passage obstruction.