AIM: To study the application of intravitreal injection of anti-vascular endothelial growth factor(VEGF)inpatients with fundus neovascularization disease in No.2 Foshan People's Hospital between 2013 to 2015.

METHODS: Retrospective analysis of inpatients of Foshan Second People's Hospital from January 2013 to December 2015, searched the inpatient management system with the term "intravitreal injection", excluded patients with intravitreal injection of TA and antibiotics, and queried the diseases involved. Then summarized the amount of inpatients of each disease as comparison.

RESULTS: Totally 239 eyes underwent injection in 3a. The proportion of male and female was even. No statistical difference among the youth,the middle age and the old group. The amount of injections was increased year by year. The main diseases underwent anti-VEGF injection was retinal vein occlusion(RVO), choroidal neovascularization retinopathy(CNV), diabetic retinopathy(DR)and polypoidal choroidal vasculopathy(PCV). Anti-VEGF injection ratio(injection/total)of the four diseases in the same year and each disease of different year were significantly statistic different. Among the four main disease, anti-VEGF injection was the most accepted in CNV patients, and anti-VEGF injection ratio was the most improved in PCV patients.

CONCLUSION: Anti-VEGF intravitreal injection as a new treatment for fundus neovascular diseases was increasingly accepted by patients.