AIM: To investigate the clinical effect of traditional Chinese medicine TQMM decoction on treating primary open angle glaucoma.

METHODS: Totally 220 patients(386 eyes)with primary open angle glaucoma in our hospital from May 2012 to January 2016 were selected. According to the order of admission they were divided into Chinese medicine group and normal group, 110 patients in each. Normal group was treated with trabeculectomy and routine treatment, traditional Chinese medicine group was given TQMM decoction for 3 courses beside the treatment of normal group(15d for a course of treatment).

RESULTS: After treatment, visual acuity of the two groups improved(P<0.05). vision sensitivity of Chinese medicine group was higher than the normal group(P<0.01); mean defect was lower than the normal group(P<0.05); central retinal artery blood PSA and EDV of Chinese medicine group were higher than those in normal group(P<0.05); RI was lower than that of normal group(P<0.05). After treatment, the total efficiency rate of Chinese medicine group was 77.8%, that was 60.8% of normal group(P<0.05).

CONCLUSION: TQMM decoction auxiliary treatment of primary open angle glaucoma is helpful to improve blood circulation, to expand visual field, and to improve the effect of treatment.