AIM: To study the effects between low concentration atropine and orthokeratology on myopia prevention and control.

METHODS: Totally 150 cases of juvenile outpatients with myopia were chosen in our hospital. They were divided into 3 groups randomly. Group A(50 cases)were treated with low concentration atropine. Group B(50 cases)were treated with orthokeratology. Group C(50 cases)were treated with spectacles. Refractive degree and ocular axial length had no statistically significant differences between three groups before treatment. After 1a follow-up, refractive degree and ocular axial length of three groups were statistically analyzed.

RESULTS: After 1a, the refractive degree changes of each group before and after treatment were statistically significant(P<0.01). The results of refractive degree changes among the groups were as follows: there was no significant differences between low concentration atropine group and orthokeratology group(P>0.05); compared with orthokeratology and low concentration atropine group, that of spectacles group was significantly different(P>0.05). After 1a follow up, the ocular axial length changes of each group before and after treatment were statistically significant(P<0.01). The results of ocular axial length changes among the groups were as follows: there was no significant differences between low concentration atropine group and orthokeratology group(P>0.05); compared with orthokeratology and low concentration atropine group, that of spectacles group was significantly different(P<0.05).

CONCLUSION: The effects of low concentration atropine and orthokeratology on controlling juvenile myopia and ocular axial length have no significant difference. They are superior to spectacles on controlling juvenile myopia.