AIM: To investigate the influence factors of phacoemulsification combined with anterior vitrectomy for treating malignant glaucoma.

METHODS: Totally 23 cases(25 eyes)of malignant glaucoma patients, who were in-patient in ophthalmology of Wuhan Tongji Hospital from June 2011 to June 2016, underwent phacoemulsification combined with anterior vitrectomy, were involved in this study. The intraocular pressure and related ocular anatomy parameter change and its correlation were analyzed pre-and post-operatively.

RESULTS: There were 15 cases(16 eyes), average 51±6.7 years old, had deepened anterior chamber and intraocular pressure within the normal range(reffered as effective)post-operatively, in the other 8 cases(9 eyes), average 45±7.8 years old, postoperative anterior chamber formation were poor(referred as ineffective). Surgery effective rate was 64%. As for the effective group, the postoperative anterior chamber depth(2.13±0.82mm), significantly deepened compared with preoperative(0.76±0.53mm), and postoperative intraocular pressure(15.4±4.5mmHg)significantly declined compared with preoperative(26.4±8.7mmHg). The effective group had larger preoperative scleral spur distance and ocular axial length than ineffective group, 11.25±0.39mm vs 10.86±0.49mm and 22.16±1.16mm vs 20.98±0.62mm respectively, and the difference was statistically significant(P<0.05). Age and the ocular axial length were statistically significant between effective and ineffective group by using single factor analysis results(P<0.05). By logistic regression analysis, age and ocular axial length were independent risk factors for poor postoperative treatment effect(P<0.05).

CONCLUSION: The younger age and the ocular axial length is risk factors for poor postoperative treatment effect of malignant glaucoma by phacoemulsification combined with anterior vitrectomy.