AIM: To observe the therapeutic effect of visual perception training combined with total nutrition meal sequential therapy in the treatment of myopic amblyopia.

METHODS: Totally 73 children(135 eyes)with myopic amblyopia were divided into control group(36 cases, 67 eyes)and treatment group(37 cases, 68 eyes)according to random number table. The control group were treated with traditional spectaculars and grating covering combined with fine eyesight training; the treatment group were treated with visual perception training combined with total nutrient meal sequential therapy. The visual acuity, diopter and average diopter of two groups were compared before and after treatment at 3, 6mo and 1a. The curative effect of two groups of children was compared after 1a treatment. And the adverse reactions were recorded in two groups during the treatment period. The recurrence rate of amblyopia in 1a follow-up was compared between two groups.

RESULTS: The difference of visual acuity between two groups was not significant at 3mo(P>0.05). The visual acuity of the treatment group was significantly higher than that of the control group at 6mo and 1a(P<0.05). There was no significant difference in diopter between the two groups after 3, 6mo and 1a(P>0.05), but the average annual refractive changes in the treatment group were significantly lower than that in the control group(P<0.05). The basic cure rate and total effective rate of the treatment group were significantly higher than that of the control group(P<0.05). There were no severe adverse reactions occurred between two groups during the treatment period. The recurrence rate of amblyopia in the treatment group was significantly lower than that in the control group(P<0.05)after 1a follow-up.

CONCLUSION: Visual perception training combined with total nutrition meal sequential therapy in the treatment of myopic amblyopia in preschool children can significantly improve patients' visual acuity, reduce the average annual diopter changes, improve the therapeutic effect, reduce the recurrence rate of amblyopia.