目的：分析江苏省阜宁县50岁及以上农村人群中年龄相关性黄斑变性(age-related macular degeneration，ARMD)的患病率情况。

方法：本项调查研究采用随机整群抽样的方法，在江苏省盐城阜宁县设置30个调查点，对50岁及以上农村人群进行视力和眼部相关检查。计量资料采用均数±标准差表示，组间比较采用独立样本t检验； 计数资料采用率或构成比表示，组间比较采用χ²检验。应用Logistic回归分析法分析年龄、性别等因素对ARMD患病率的影响。

结果：随机抽样6 145例，实际纳入5 947例，受检率为96.78%。检出ARMD患者448例633眼，患病率为7.53%。按日常生活视力(PVA)和视力损伤标准计算，在中重度视力损伤和盲眼中，由ARMD引起的中重度视力损失和盲分别占11.96%和 4.13%； 按最佳矫正视力(BCVA)和视力损伤标准计算，在中重度视力损伤和盲眼中，由ARMD引起的中重度视力损伤和盲分别占7.79%和4.45%。高龄是影响ARMD的相关因素(OR=1.01，P=0.040)。

结论：江苏省阜宁县农村50岁及以上人群中，ARMD患病率较高，是影响老年人视力的主要原因之一。

METHODS: Survey research. Random cluster sampling was used in selecting individuals aged ≥50 years in 30 clusters in Funing county. Proportions were compared by using the χ² test and the means compared by using the t-test. Logistic regression was used to detect possible factors of ARMD such as age and gender.

RESULTS: A total of 6 145 persons aged 50 years were enumerated and 5 947(96.78%)participants were received visual acuity test and eye examination. The prevalence of ARMD was 7.53%, with a total of 448 individuals(633 eyes). The prevalence of blindness and visual impairment for presenting visual acuity were 4.13% and 11.96%, respectively. The prevalence of blindness and visual impairment for presenting visual acuity were 4.45% and 7.79%, respectively. Older were significant risk factors of ARMD(OR=1.01, P=0.04).

CONCLUSION: The prevalence of ARMD was higher among people aged 50 years and above in Funing county, Jiangsu province. ARMD is one of the leading cause of visual impairment.