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[摘要]
目的:评估特发性视网膜前膜术后视力恢复的两种预测因素。
方法:回顾性研究2014-01/2016-10在我院行玻璃体切割联合黄斑前膜剥除术的30例30眼特发性视网膜前膜病例资料,评估光学相干断层扫描(OCT)相关参数,记录术前、术后1、3、6mo的最佳矫正视力(BCVA),探讨最终最佳矫正视力与黄斑中心光感受器细胞层(椭圆体带)完整性或光感受器外节长度的相关性。
结果:特发性视网膜前膜术后1mo最佳矫正视力较术前降低,术后3、6mo逐渐好转并提高; 黄斑中心厚度在术后1mo较术前增厚,术后6mo明显缓解(P<0.05); 而光感受器外节长度在术后1mo较术前缩短(P<0.05),术后3、6mo接近术前。多元线性回归分析中最终最佳矫正视力与黄斑中心光感受器细胞层完整性和光感受器外节长度明显相关(P=0.023、0.004)。
结论:黄斑中心光感受器细胞层完整性和光感受器外节长度均可预测特发性视网膜前膜术后最佳矫正视力。
[Key word]
[Abstract]
AIM: To evaluate two structural predictors of visual outcome of epiretinal membrane surgery.
METHODS: Retrospective study for 30 eyes of epiretinal membrane surgery between January 2014 and October 2016. We assessed the related parameters of the optical coherence tomography and recorded the best-corrected visual acuity(BCVA)at baseline and 1, 3 and 6mo after surgery. Correlations between the final best-corrected visual acuity and photoreceptor integrity status or photoreceptor outer segment length were investigated.
RESULTS: Average best-corrected visual acuity decreased at 1mo postoperatively compared with baseline, but improved at 3 and 6mo. Central macular were more sweller at 1mo postoperatively than baseline, but a significant thickeness reduction was found at 6mo(P<0.05). Photoreceptor outer segment length were shortened at 1mo compared with preoperation(P<0.05), gradually approached the baseline level at 3 and 6mo. Multivariate regression the final best-corrected visual acuity associated with photoreceptor integrity and photoreceptor outer segment length(P=0.023, 0.004).
CONCLUSION: Photoreceptor integrity and photoreceptor outer segment length detected by OCT were significant predictors of the final best-corrected visual acuity(BCVA)after idiopathic epiretinal membrane surgery.
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