AIM: To study and compare the influence situation of corneal flap made by microkeratome and femtosecond laser for the vision and corneal flap thickness in patients.

METHODS: Totally 120 patients(240 eyes)with myopic refractive surgery in our hospital from June 2014 to May 2015 were randomly divided into Group A(microkeratome group)with 60 cases(120 eyes)and Group B(femtosecond laser group)with 60 cases(120 eyes). Then the vision situation and corneal flap thickness indexes of two groups at different time after the treatment were compared.

RESULTS: The vision situation between the two groups at different time after the treatment all had no significant differences(all P>0.05), while the corneal flap thickness related indexes of Group B at different time after the treatment were all better than those of Group A(all P<0.05). The evaluation indexes of two groups after the treatment all had significant differences(all P<0.05).

CONCLUSION: The indexes of corneal flap made by femtosecond laser are better than those of microkeratome, and the influence of two methods for the vision is no obvious.