AIM: To explore the effect of vitrectomy combined with gas-liquid exchange on the treatment of posterior segment nonmagnetic foreign body and best corrected visual acuity(BCVA)after operation.

METHODS: Totally 84 patients(86 eyes)were enrolled in this study. They were divided into observation group and control group, each group with 42 cases(43 eyes). The control group was treated with vitrectomy alone, and the observation group was treated with gas-liquid exchange combined with vitrectomy. The operation time, foreign body clearance rate, retinal recovery rate, BCVA level, macular central retinal thickness, and complications were compared between two groups.

RESULTS: The operation time and complication rate of the observation group were lower than those of the control group. The rate of foreign body clearance and retinal reattachment was higher than that of the control group(P<0.05). The BCVA and macular center retinal thickness were lower in the observation group than in the control group at each time point(P<0.05).

CONCLUSION:Gas-liquid exchange combined with vitrectomy for the treatment of non-magnetic foreign bodies in the posterior segment of the eye is effective, which can improve the postoperative visual acuity, the retinal edema and reduce surgical complications.