飞秒激光辅助超声乳化白内障吸除术角膜切口的形态学改变
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广东省医学科学技术研究基金项目(No.C2017029); 广州市医药卫生科技项目(No.20161A011097)


Morphological changes of corneal incision in femtosecond laser-assisted phacoemulsification
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Medical Science and Technology Research Foundation Project of Guangdong Province(No.C2017029); Guangzhou Medical and Health Science and Technology Research(No.20161A011097)

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    摘要:

    目的:观察飞秒激光辅助超声乳化白内障吸除术(2.4mm微切口)及传统超声乳化白内障吸除术(2.4mm微切口)角膜切口的形态学的改变,评估两者切口的稳定性。

    方法:本研究为前瞻性对照研究。患者89例99眼接受白内障手术,根据术式分为两组:飞秒激光组:飞秒激光超声乳化手术组44例49眼; 角膜刀组:2.4mm白内障超声乳化手术组45例50眼。术后应用OCTA评估角膜切口形态改变。

    结果:术后1d飞秒激光组未发现外切口哆开,角膜刀组发生率为10%(P<0.05); 术后1wk,1、3mo两组均未见外切口哆开。术后1wk,1mo飞秒激光组内切口哆开的发生率分别为47%、10%,均低于角膜刀组(术后1wk为68%,1mo为26%)(P<0.05),术后1d,3mo两组无差异。两组各时间点局部后弹力层脱离的发生率均无差异。

    结论:飞秒激光辅助超声乳化白内障吸除术角膜切口早期愈合更好,有效减少早期角膜切口异常构筑的发生。

    Abstract:

    AIM: To observe the morphology of corneal incision between femtosecond laser-assisted cataract surgery(FLACS)with 2.4mm micro-incision and conventional phacoemulsification cataract surgery(CPCS)with 2.4mm micro-incision, evaluating the safety and stability of the incision.

    METHODS: This was a prospective controlled study. A total of 89 cataract patients(99 eyes)who underwent cataract surgery were collected. All patients were divided into two groups: 44 cases(49 eyes)in FLACS group and 45 cases(50 eyes)in CPCS group. Morphology of clear corneal incision was observed by OCTA postoperative.

    RESULTS: There was no external wound dehiscence in FLACS group on 1d postoperative, while 10% patients had external wound dehiscence in CPCS group(P<0.05). There were no external wound dehiscence in both groups on 1wk, 1mo and 3mo postoperative. On 1wk and 1mo postoperative, the incidences of internal wound dehiscence in FLACS group(47% of 1wk and 10% of 1mo)were lower than that in CPCS group. There were statistically significant difference(68% of 1wk and 26% of 1mo)(P<0.05). On 1d and 3mo postoperative, there were no significant difference in internal wound dehiscence in both groups. There were no significant differences in descemet membrane detachment(DMD)in both groups.

    CONCLUSION: Femtosecond laser-assisted cataract surgery(FLACS)is benefit for wound closure and reducing abnormal incision construction.

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何曼莎,武哲明,陈韵,等.飞秒激光辅助超声乳化白内障吸除术角膜切口的形态学改变.国际眼科杂志, 2019,19(6):1039-1043.

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  • 收稿日期:2019-01-21
  • 最后修改日期:2019-04-29
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  • 在线发布日期: 2019-05-22
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