目的：探讨糖尿病视网膜病变(DR)患者全视网膜激光光凝术(PRP)术后预后相关影响因素。

方法：收集2015-09/2017-09来我院就诊的DR患者182例301眼，根据病变分期给予患者不同的治疗方式，增殖前期患者进行次全视网膜光凝治疗，DR增殖早期患者进行标准全视网膜光凝治疗，高危患者进行超全视网膜光凝治疗。对患者随访6mo，记录患者的预后情况，筛选对视力变化有影响的相关因素。

结果：对单因素有意义的因素进行多因素Logistic回归分析可以得出，年龄、初诊视力、低密度脂蛋白胆固醇、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、糖化血红蛋白、黄斑水肿严重程度、血压与预后具有相关性(P<0.05)。

结论：高血压、年龄大、高血脂、初诊视力差、糖化血红蛋白水平高、黄斑水肿严重对DR患者激光光凝术后的预后造成一定影响。

METHODS: Totally 182 patients(301 eyes)with DR from September 2015 to September 2017 in our hospital were collected. Preoperative automatic biochemical analyzer was used to examine blood biochemical indicators. According to the stage of disease, different treatments were given. Patients with early proliferative DR were underwent standard panretinal photocoagulation and suprahepatic retinal photocoagulation at high-risk. After 6mo follow-up of patients, record the prognosis of patients, screening for changes in visual acuity related factors.

RESULTS: Multivariate Logistic regression analysis showed that age, visual acuity at first visit, low density lipoprotein cholesterol, total cholesterol, triglyceride, high density lipoprotein cholesterol, glycosylated hemoglobin, severity of macular edema, hypertension and prognosis were correlated(P<0.05).

CONCLUSION: Hypertension, age, hyperlipidemia, poor initial vision, high level of glycosylated hemoglobin and severe macular edema have some effects on the prognosis of DR patients after laser photocoagulation.