AIM: To investigate the prognostic factors associated with panretinal laser photocoagulation in patients with diabetic retinopathy(DR).

METHODS: Totally 182 patients(301 eyes)with DR from September 2015 to September 2017 in our hospital were collected. Preoperative automatic biochemical analyzer was used to examine blood biochemical indicators. According to the stage of disease, different treatments were given. Patients with early proliferative DR were underwent standard panretinal photocoagulation and suprahepatic retinal photocoagulation at high-risk. After 6mo follow-up of patients, record the prognosis of patients, screening for changes in visual acuity related factors.

RESULTS: Multivariate Logistic regression analysis showed that age, visual acuity at first visit, low density lipoprotein cholesterol, total cholesterol, triglyceride, high density lipoprotein cholesterol, glycosylated hemoglobin, severity of macular edema, hypertension and prognosis were correlated(P<0.05).

CONCLUSION: Hypertension, age, hyperlipidemia, poor initial vision, high level of glycosylated hemoglobin and severe macular edema have some effects on the prognosis of DR patients after laser photocoagulation.