目的：比较白内障患者植入衍射型非球面双焦点IOL和非球面单焦点IOL术后的视觉质量和视觉相关生活质量。

方法：回顾性非随机研究，收集2016-10/2017-12行白内障超声乳化联合IOL植入术患者110例176眼，其中植入衍射型非球面双焦点IOL(ZEISS AT LISE 809M)56例82眼，植入非球面单焦点IOL(ZEISS CTA 603P)54例94眼。术后随访时间3mo，主要观察指标包括：视力、客观视觉质量分析系统\〖调制传递函数截止空间频率(MTF cutoff)、斯特列尔比(SR)、客观散射指数(OSI)、3种对比度下的视力(100%VA、20%VA、9%VA)\〗和视功能相关的生存质量量表(NEI-VFQ-25)。

结果：(1)视力：两组患者术后矫正远视力无差异(P>0.05)，而术后矫正远视力下的近视力有差异(P<0.01)。(2)客观视觉质量分析：两组患者术后平均OSI值、20%VA和9%VA有差异(P<0.01)。(3)NEI-VFQ-25调查表11个亚项中，两组患者在整体健康、总体视力、眼痛、远视力、周边视野、社会功能、色觉、依赖程度、精神健康方面无差异(P=0.88、0.08、0.60、0.36、0.80、0.18、0.41、0.07、0.95)，在近视力、社会角色限制方面有差异(P<0.05)。

结论：两种IOL均能提高患者术后视觉质量，衍射型非球面双焦点IOL能提供更好的近视力，但是OSI较非球面单焦点IOL增加，可能会出现一定的视觉干扰。术后视功能相关的生存质量总体无差异。

METHODS: Retrospective non-randomized study was implemented. In clinical application 110 patients(176 eyes)underwent phacoemulsification combined with IOL from October 2016 to December 2017. In details, 56 cases(82 eyes)with diffractive aspheric bifocal IOL(ZEISS AT LISE 809M)and 54 cases(94 eyes)with single focus aspheric IOL(ZEISS CTA 603P), respectively. Three months after surgeries, the main evaluation indices were successively collected, which included visual, the optical quality analysis system(OQAS)of the MTF cutoff, the Strehl ratio, the OSI, the 100% visual acuity(VA), the 20% VA and the 9% VA, as well as the visual function related quality of life scale(NEI-VFQ-25).

RESULTS: 1)VA: there was no significant difference in the corrected distance visual acuity(CDVA)between the two groups(P>0.05). However, there existed significant difference in the near vision(P<0.05); 2)Objective quality visual analysis(OQAS): there was significant difference in the OSI. Regarding the visual acuity of simulated contrast sensitivity between two groups, the 20% VA and 9% VA expressed significant difference(P<0.01); 3)NEI-VFQ-25 questionnaire: there were no significant differences in overall health, general vision, eye pain, distant vision, peripheral vision, social function, color vision, dependence and mental health between the two groups(P=0.88, 0.08, 0.60, 0.36, 0.80, 0.18, 0.41, 0.07, 0.95). But there was significant difference in near vision and social role limitation between the two groups(P<0.05).

CONCLUSION: The 809M intraocular lenses and the 603P intraocular lenses can improve the optical quality of patients after the surgeries. The former one can provide better near vision, but the OSI was higher than the latter one, which may cause some visual interference. There was no significant difference in visual related quality of life after the surgeries generally.