方法：将2017-12/2018-06在我院眼科需要行眼底激光治疗的56例糖尿病视网膜病变Ⅲ期患者随机分为两组：试验组(芪明颗粒联合眼底激光治疗)28例， 对照组(眼底激光治疗)28例。观察两组治疗后视力(BCVA)，平均视野缺损(MD)，黄斑中心厚度(CMT)的改变，观察时间为6mo。

结果：治疗后1、3、6mo试验组、对照组患眼平均BCVA、MD值、CMT值与治疗前比较均有差异(P<0.05)。治疗后1、3mo两组患眼平均BCVA、MD值、CMT值比较均有差异(P<0.05)； 治疗后6mo均无差异(P>0.05)。

结论：芪明颗粒短期内可减轻激光光凝对视网膜功能损害程度，促使激光损伤的快速修复，减轻糖尿病性黄斑水肿。

METHODS: Fifty six patients with Ⅲ stage diabetic retinopathy who were treated in our hospital from December 2017 to June 2018 were divided into control group(28 cases)and observation group(28 cases)according to the treatment method. The control group was treated with panretinal photocoagulation. The observation group was treated with Qi Ming granule combined with retinal laser photocoagulation. The best-corrected visual acuity(BCVA), mean defect of visual field(MD), and central macular thickness(CMT)were examined before photocoagulation and 1mo, 3mo and 6mo after photocoagulation to compare the retinal function between the two groups.

RESULTS: The mean BCVA, MD and CMT values of the eyes in the PRP+ drug treatment group and the PRP treatment group were statistically significant(P<0.05)at 1, 3, and 6mo after treatment. The mean BCVA, MD and CMT values between the two groups were statistically significant(P<0.05)at 1 and 3mo after treatment. There was no significant difference at 6mo after treatment(P>0.05).

CONCLUSION: Qi Ming granule can alleviate the degree of laser photocoagulation damage to the retina, promote the rapid repair of laser damage, and reduce diabetic macular edema. It is worthy of popularization and application in the clinic.