[关键词]
[摘要]
随着科学的发展和社会的进步，近年关于原发性青光眼眼底血流动力学的研究有了革命性的突破，诞生了一种非侵入性的影像学辅助检查方法—光学相干断层扫描血管成像技术(OCTA)。该技术与传统的检查方法相比具有很多优点，其利用分频谱振幅去相关血管成像(SSADA)的方式获取眼底三维立体血流图像，可以分层并量化眼底血流密度，具有无创、迅速、可重复、分层成像和高分辨率等特点，可用于监测青光眼眼底血流的早期改变、病情进展及疗效评估。但OCTA在临床实际应用中目前还存在一定的缺陷，需要进一步研究，才能更广泛地应用于青光眼疾病的更多领域，本文就OCTA技术在原发性青光眼中的应用及研究进展做一综述。
[Key word]
[Abstract]
With the development of science and the progress of society,a revolutionary breakthrough-optical coherence tomography angiography(OCTA), a non-invasive imaging-assisted examination method-has been achieved, in the study of hemodynamics of the fundus of primary glaucoma in recent years. This technology has many advantages compared with previous traditional inspection methods. It fully exercises split-spectrum amplitude decorrelation angiography(SSADA)to acquire three-dimensional blood flow images of the fundus. With characteristics of none invasion but fastness, repeatability, layered imaging and high resolution, it can stratify and quantify the fundus blood flow density, and is also used to monitor the early changes of glaucoma fundus blood flow, disease progression and evaluation of therapeutic effect. However, OCTA presents certain shortcomings in actual clinical applications. Before available to function more widely in the fields of glaucoma disease, this method demands further researches and development. This article gives an overview of the application and research progress of OCTA technology in primary glaucoma.
[中图分类号]
[基金项目]
国家自然科学基金项目(No.81100665,81770929); 陕西省教育厅2018年服务地方科学研究计划项目(No.18JC026); 陕西省科技厅项目(No.2019SF-162)
