目的：比较两种散光矫正型人工晶状体治疗合并角膜散光白内障的临床效果。方法：回顾分析2019-04/07在北医三院行眼科手术的35例50眼合并角膜散光的白内障患者，其中，20例25眼植入散光矫正型人工晶状体623T(Rayner组)，15例25眼植入散光矫正型人工晶状体Acrysof Toric(Alcon组)。比较术后3mo，两组患者的裸眼远视力、最佳矫正远视力、残余散光度、人工晶状体旋转度数、对比敏感度、客观视觉质量(调制传递函数截止频率、斯特列尔比、客观散射指数、不同对比度下的客观视力)、NEI VFQ-25量表评分的差异。散光矢量分析运用Alpins分析法。结果：Rayner组术后平均裸眼远视力和最佳矫正远视力(LogMAR)分别为0.17±0.20和0.08±0.15，Alcon组分别为0.21±0.16和0.10±0.11(P>0.05)； Rayner组术后平均残余散光度为(-0.57±0.24)D，Alcon组为(-0.50±0.28)D(P>0.05)； 两组术后3mo人工晶状体旋转稳定性、散光矢量分析、各空间频率下对比敏感度、客观视觉质量各指标差异无统计学意义(P>0.05)。Rayner组NEI VFQ-25量表评分为85.16±5.91，Alcon组为82.08±6.16(P>0.05)。结论：两种散光矫正型人工晶状体Rayner 623T和Alcon Acrysof Toric治疗合并角膜散光白内障患者的临床效果并无显著差异。

AIM: To compare the clinical effects of two brands of Toric intraocular lens(IOL)used in surgical correction of cataract with corneal astigmatism.METHODS: Totally 35 patients(50 eyes)with corneal astigmatism who underwent ophthalmic surgery from April 2019 to July 2019 were retrospectively analyzed. Among them, 25 eyes of 20 patients were implanted with Rayner 623T, while 25 eyes of 15 patients with Alcon AcrySof Toric IOL. Three months after surgery, the uncorrected distance visual acuity(UCDVA), best corrected distance visual acuity(BCDVA), residual astigmatism, rotational degree of intraocular lens, contrast sensitivity, objective visual quality and the National Eye Institute 25-Item Visual Function Questionnaire(NEI VFQ-25)scale score were compared. Vector analysis was performed using the Alpins method.RESULTS: The mean postoperative UCDVA(LogMAR)and BCDVA(LogMAR)in the Rayner group were 0.17±0.20 and 0.08±0.15, respectively(P>0.05), while those in the Alcon group were 0.21±0.16 and 0.10±0.11, respectively(P>0.05). The mean residual astigmatism in the Rayner group was(-0.57±0.24)D while that in the Alcon group was(-0.50±0.28)D(P>0.05). There was no statistically significant difference between the two groups in IOL rotational stability, vector analysis parameters, contrast sensitivity and objective visual quality(P>0.05). The NEI VFQ-25 scale score was 85.16±5.91 in the Rayner group while it was 82.08±6.16 in the Alcon group(P>0.05).CONCLUSION: The two brands of Toric IOL-Rayner 623T and Alcon AcrySof Toric showed no significant difference in their clinical outcomes.