目的：观察区域折射型多焦点人工晶状体(MIOL)SBL-3植入术后视觉质量。

方法：回顾性对照研究南昌大学第二附属医院2019-09/2020-07收治的57例68眼白内障患者。其中植入区域折射型MIOL SBL-3者33例36眼(SBL-3组)，植入非球面单焦点人工晶状体(SIOL)ZCB00者24例32眼(ZCB00组)，对比两组术后3mo裸眼和矫正远、中、近视力、离焦曲线、OPDIII客观视觉质量、QoV问卷调查、患者满意度及术后脱镜率。

结果：术后3mo SBL-3组和ZCB00组裸眼和矫正远视力LogMAR值(0.13±0.09 vs 0.10±0.08，0.06±0.06 vs 0.08±0.08，均P>0.05)无显著差异，裸眼远视力均较术前有显著改善(P<0.05)。SBL-3组裸眼及最佳矫正远视力下的中、近视力明显优于ZCB00组(0.10±0.14 vs 0.27±0.10，0.05±0.16 vs 0.35±0.17，0.11±0.14 vs 0.26±0.11，0.03±0.17 vs 0.35±0.17，均P<0.05)。在所评估的各个空间频率上患者对比敏感度的比较中ZCB00组均优于SBL-3组(P<0.05)。SBL-3组总像差、总高阶像差、彗差、三叶草差均大于ZCB00组且有显著差异(P<0.05)，SBL-3组平均SR值小于ZCB00组(P<0.05)。术后3mo SBL-3组出现眩光1例，光晕1例，视远模糊4例。SBL-3组和ZCB00组患者表示非常满意者分别占82%、88%。两组间满意度比较无显著差异(P>0.05)，脱镜率(94% vs 67%)比较有显著差异(P<0.05)，且SBL-3组脱镜率更高。

结论：新型区域折射型MIOL SBL-3提供了良好的全程视力，术后不良视觉症状少，满意度和脱镜率高。

METHODS: A retrospective and controlled study. Fifty-seven cataract patients(68 eyes)in our hospital from September 2019 to July 2020 were enrolled. Totally 33 cases(36 eyes)received regional refractive MIOL SBL-3(SBL-3 group), while 24 cases(32 eyes)received aspheric single focal intraocular lens(SIOL)ZCB00(ZCB00 group). Uncorrected and corrected distance, middle and near visual acuity, defocus curve, OPDⅢ objective visual quality, the quality of vision(QoV)questionnaire, patient satisfaction and spectacle independence were evaluated 3mo postoperatively.

RESULTS: No significant differences were found between the SBL-3 group and the ZCB00 group in terms of LogMAR value of corrected and uncorrected distance visual acuity(UDVA)at 3mo after the operation(0.13±0.09 vs 0.10±0.08, 0.06±0.06 vs 0.08±0.08, all P>0.05)and the UDVA was significantly improved compared with that before the operation(P<0.05). Corrected and uncorrected intermediate and near visual acuity were significantly better for the SBL-3 group than the ZCB00 group(0.10±0.14 vs 0.27±0.10, 0.05±0.16 vs 0.35±0.17, 0.11±0.14 vs 0.26±0.11, 0.03±0.17 vs 0.35±0.17, all P<0.05). Concerning the comparison of contrast sensitivity, the ZCB00 group was better than SBL-3 group at any spatial frequency evaluated and the differences were significant(all P<0.05). Statistically significant differences between groups were observed in intraocular total aberrations, high-order aberrations, coma and Trefoil presenting significantly higher values in the eyes of the SBL-3 group than in the ZCB00 group(P<0.05). The average Strehl ratio value was smaller in the ZCB00 group and the difference was statistically significant(P<0.05). There were 1 patient who had glare, 1 patient reported halo, 4 patients complained distance blur in the SBL-3 group at 3mo after the surgery. 82% and 88% were completely satisfied in the SBL-3 group and ZCB00 group, respectively. There was no statistically significant difference in satisfaction between the groups. SBL-3 group had a higher percentage of spectacle independence and the difference was significant(94% vs 67%, P<0.05).

CONCLUSION:The regional refractive MIOL SBL-3 provided good range of vision for near, intermediate, and distance. Although few vision phenomena were reported, it resulted in an excellent level of overall patient satisfaction and freedom from spectacles.