方法：回顾性分析2019-06/2020-12在我院就诊的晶状体半脱位引起的ASAC患者15例15眼，对患者行晶状体超声乳化摘除联合Yamane巩膜层间IOL固定术治疗。随访3mo，观察患者的眼压、最佳矫正视力(BCVA)、术后IOL位置和并发症情况。

结果：所有患者均顺利完成手术，术后眼压较术前下降，术前和术后1d，1wk，1、3mo的眼压比较总体有差异(F=165.57，P<0.001)，进一步两两比较发现术后1d，1wk，1、3mo的眼压与术前比较均有差异(均P<0.001)，术后1wk，1、3mo的眼压均在正常范围； 术后3mo的BCVA优于术前(t=10.717，P<0.001)； 所有IOL未见明显偏位，术后未发生严重并发症。

结论：通过晶状体超声乳化摘除联合Yamane技术治疗晶状体半脱位引起的ASAC可有效控制眼压，提高视力，且术后IOL位置稳定并减少并发症。

METHODS: Clinical data of 15 patients(15 eyes)with ASAC caused by lens subluxation who underwent phacoemulsification combined with intrascleral fixation of IOL by using Yamane's technique from June 2019 to December 2020 were reviewed retrospectively. The patients were followed for 3mo. The preoperative and postoperative intraocular pressure(IOP), best corrected visual acuity(BCVA), positions of the IOL and complications were observed.

RESULTS: All the operations were successfully completed. The postoperative IOPs were lower than preoperative IOPs. There were overall differences between preoperative and postoperative IOPs(F=165.57, P<0.001). Through further pairwise comparison, the IOPs at 1d, 1wk, 1, and 3mo after operation were significantly different from IOPs before operation(all P<0.001). The IOPs remained normal range at 1wk, 1, and 3mo after operation. The BCVA at 3mo after operation was significantly better than the preoperative BCVA(t=10.717, P<0.001). All IOLs were in the expected position without an obvious tilt or displacement. No serious complications occurred after the operation.

CONCLUSION: The surgical strategy of phacoemulsification combined with intrascleral fixation of IOL by using Yamane's technique in the treatment of ASAC caused by lens subluxation was safe and effective by lowing IOP, rescuing visual, maintaining stability of IOL and reducing complications.