方法：选取2020-06/2021-06在我院行白内障手术的患者157例157眼，根据术前角膜曲率(K)分为3组，A组(53眼)K<42D，B组(55眼)42D≤K≤46D，C组(49眼)K>46D。术前分别采用SRK/T、Hoffer Q、Holladay 2、Haigis、Kane、BarrettⅡ公式计算IOL屈光度，术后1mo行主觉验光检查，计算并分析三组患者屈光预测误差(RPE)和平均绝对值误差(MAE)的差异。

结果：A、C组每个公式的RPE与0D比较均有差异(P<0.05)，且BarrettⅡ公式与SRK/T、Hoffer Q、Holladay 2、Haigis公式比较均有差异(P<0.01)，与Kane公式比较无差异(P>0.01)； B组所有公式的RPE与0D比较均无差异(P>0.05)。A组BarrettⅡ公式MAE≤0.5D的比率显著高于SRK/T、Hoffer Q、Holladay 2、Haigis公式(均P<0.01)，但与Kane公式比较无差异(P>0.01)； B组BarrettⅡ公式的MAE≤0.5D和≤1.0D的比率与其他公式比较无差异(均P>0.01)； C组Barrett Ⅱ公式MAE≤0.5D的比率高于SRK/T和Hoff Q公式(均P<0.01)，但在MAE≤1.0D的比率与其他公式均无差异(P>0.01)。

结论：当术前K<42D或K>46D，常用IOL屈光度计算公式均会产生屈光误差，但Kane和BarrettⅡ公式的准确性依然高于其他公式。

METHODS:Totally 157 cases(157 eyes)with age related cataract were collected in Kaifeng Central Hospital from June 2020 to June 2021. Patients were divided into 3 groups according to keratometry: group A(53 eyes)(K<42D), group B(55 eyes)(42D≤K≤46D), group C(49 eyes)(K>46D). The IOL diopter was calculated by SRK/T, Hoffer Q, Holladay 2, Haigis, Kane and Barrett Ⅱ formulas respectively. Subjective optometry was performed after 1mo operation. The average refractive prediction error(RPE)and mean absolute error(MAE)were calculated, and their differences were compared and analyzed.

RESULTS:There were significant difference between RPE of each formula and 0D in groups A and C(P<0.05), and Barrett Ⅱ formula was significantly different with SRK/T, Hoffer Q, Holladay 2 and Haigis formula(P<0.01), but was no significantly different with Kane formula in RPE(P>0.01). There was no significant difference in RPE between group B and 0D(P>0.05). The ratio of Barrett Ⅱ formula in MAE≤0.5D in group A was significantly higher than SRK/T, Hoffer Q, Holladay 2 and Haigis formula(all P<0.01), but there was no significant difference compared with Kane formula(P>0.01). In group B, there was no significant difference among Barrett Ⅱ formula and the other formulas in the ratio of MAE≤0.5D and ≤1.0D(all P >0.01). In group C, the ratio of SRK/T and Hoff Q formula in MAE≤0.5D was lower than Barrett Ⅱ formula(all P<0.01), and there were no significant difference among Barrett Ⅱ formula and the other formulas in the ratio of MAE≤1.0D(P >0.01).

CONCLUSION:If K<42D or K>46D before operation, the commonly used formulas will produce refractive error, but the accuracy of Kane and Barrett Ⅱ formulas are still higher than other formulas.