AIM: To observe the dynamic changes of lens parameters of adolescents with hyperopia and myopia, analyze the difference to investigate the characteristics of lens changes under different accommodation stimuli.

METHODS: A random selection of 50 cases(86 eyes)of adolescents with refractive errors aged 7-15 years old who visited our clinic from January to October 2019 were divided into in myopia group(29 cases, 46 eyes, mean equivalent spherical lens was -2.17±1.41D)and hyperopia group(21 cases, 40 eyes, mean equivalent spherical lens was 1.92±1.49D). The axial length(AL)was measured by optical biometer(IOL Master). By using anterior swept source optical coherence tomography(SS-OCT), the dynamic changes of lens parameters including lens thickness(LT), anterior crystalline lens radius of curvature(ALRC)and posterior crystalline lens radius of curvature(PLRC)were observed under different accommodation stimuli(0, -3, -6D).

RESULTS: In the state of relaxed accommodation(0D), the LT of the myopia group was significantly lower than that of the hyperopia group, both ALRC and PLRC were greater than those of the hyperopia group(all P<0.01). The AL of the hyperopia group was significantly shorter than that of the myopia group(22.49±1.12mm vs 24.48±0.82mm, P<0.01). With the increase of the accommodation stimulus amplitudes(-3, -6D), the LT of the two groups increased significantly, the ALRC and PLRC both decreased significantly(all P<0.01). Under the condition of -3D and -6D, the change rate of ALRC was higher than that of PLRC in both groups(P<0.01). However, the change rate of LT and PLRC were not significantly different between the two groups(P>0.05). Furthermore, the change rate of ALRC in the hyperopia group was significantly higher than that of the myopia group when the -6D accommodation was completed(P<0.05).

CONCLUSION: During accommodation stimulation, the thickness of the lens in adolescents with refractive errors increased, the shape of the lens became convex, and the degree of change of the anterior surface was significantly greater than that of the posterior surface.