Lattice degeneration of the retina(LD)is a peripheral vitreoretinal lesion characterized by atrophic retinal lesions and vitreous liquefaction in the equatorial region of the fundus. The progress of the disease is slow and the pathogenesis is not clear, which may be the result of multiple factors, among which the increase of ocular axis is one of the main risk factors. With the increase of myopia incidence, the prevalence of LD is on the rise. In recent years,it has become possible to quickly examine peripheral retina with the development of ultra-wide field fundus imaging technology. At present, retinal photocoagulation is the main prevention and treatment method for LD, but the need for preventive treatment is still unclear. This article reviews the epidemiology, pathogenesis, influencing factors and treatment of LD, hoping to provide ideas for further research and treatment of myopia-related LD.