[关键词]
[摘要]
儿童青光眼是一类难治性青光眼，微创青光眼手术(MIGS)为儿童青光眼提供了安全有效的治疗选择。多数已发表的研究倾向于支持应用全周内路小梁切开术，其治疗儿童青光眼的安全性和有效性与非MIGS的全周外路小梁切开术相似。关于KDB刀、小梁消融术和Xen凝胶支架的研究较为有限，但在某些特定的病例中可能有其各自的优势。每一种MIGS手术在考虑其优势之处的同时须特别权衡每种手术方法的长期效果。此外，还需要更多的前瞻性和比较性研究、更大的样本量和更长的随访时间来验证MIGS手术治疗儿童青光眼的安全性和有效性。
[Key word]
[Abstract]
Childhood glaucoma is a kind of refractory glaucoma. Minimally invasive glaucoma surgery(MIGS)provides a safe and effective treatment option for childhood glaucoma. Most of the published studies tend to be with circumferential ab interno trabeculotomy, showing that its safety and effectiveness in the treatment of childhood glaucoma are comparable to non-MIGS circumferential ab externo trabeculotomy. Studies on KDB, trabectome and Xen-gel stent are relatively limited, but they may have advantages in some specific cases. While considering the advantages of each MIGs operation, it is also necessary to weigh the long-term effect of each operation method. In addition, more prospective and comparative researches, larger sample size and longer follow-up time are needed to verify the safety and effectiveness of MIGs in the treatment of childhood glaucoma.
[中图分类号]
[基金项目]
国家自然科学基金项目(No.81170841); 福建省自然科学基金项目(No.2011D001); 福建省医学创新项目(No.2011-CXB-47); 华厦转化医学青年基金项目(No.2017-A-00301)
