[关键词]
[摘要]
眼外肌手术作为斜视治疗最主要的方式，可以达到矫正眼位、改善外观、重建三级视功能的目的。既往研究发现眼外肌术后早期视网膜血流密度(VD)及厚度增加，并涉及多种机制参与。近年来，随着光学相干断层扫描血流成像技术(OCTA)等检测手段出现，让我们对传统眼外肌术式带来的视网膜微观改变及其机制的量化认识越来越深刻，术后早期视网膜VD增加可能与术后视功能的恢复密切相关，但目前相关研究较少，眼外肌术后视网膜微观变化与视功能之间的关联及影响机制尚需进一步明确，本文将从多角度对眼外肌术后视网膜微观变化及其机制进行综述，提高对其影响机制及与视功能之间关联的认识，以期为眼外肌手术方案的选择及相关临床研究提供借鉴。
[Key word]
[Abstract]
As a primary treatment for strabismus, extraocular muscle surgery can achieve the purpose of correcting the eye position, improving the appearance and reconstructing the third-level visual function. Previous studies have found that the vascular density(VD)and thickness of retina increased in the early stage after extraocular muscle surgery, where multiple mechanisms involved. In recent years, with the appearance of detection means such as optical coherence tomography angiography(OCTA), our quantitative understanding of retinal microscopic changes and their mechanisms brought about by traditional extraocular muscle surgery has become more and more profound. The increase of retinal VD in the early postoperative period may be closely related to the recovery of postoperative visual function. However, the related studies are few, and the association between microscopic changes and visual function after extraocular muscle surgery and its mechanism need to be further clarified. This article will review the microscopic changes of retina and their mechanisms after extraocular muscle surgery from multiple perspectives to improve our understanding of the relationship between the mechanism of its influence and visual function, with a view to provide references for the choice of extraocular muscle surgery scheme and related clinical research.
[中图分类号]
[基金项目]
成都中医药大学2021年度“杏林学者”学科人才科研提升计划(No.YYZX2021108)
