[关键词]
[摘要]
非特异性眼眶炎症(NSOI)是一种病因不明的眼眶炎症性改变，特征性临床表现包括眼部疼痛、眼球突出、眶周充血、水肿、复视和视觉障碍等。NSOI是一种排他性诊断，没有具体的诊断标准或治疗指南，需要排除所有特异性炎性反应病因(包括感染性、血管性、肿瘤性、肉芽肿性及IgG4相关性眼病等)及其他症状类似的系统性疾病后方可确诊，也可通过眼眶活检标本中出现炎性细胞浸润、纤维化等病理改变确诊，因此被认为是眼眶活检中最常见的诊断。NSOI不典型的症状和体征，使其诊断和治疗均面临巨大挑战。本指南由中国医师协会眼科分会眼肿瘤专委会、国际智能医学会眼科专业委员会、国际转化医学会眼科专业委员会主持制订，对NSOI的定义、分类、诊断和治疗做了详细的介绍，旨在帮助临床医师提高其诊断效能，更快、更好地为患者制定诊疗计划。
[Key word]
[Abstract]
Nonspecific orbital inflammation(NSOI)is an orbital inflammation that is not associated with an infection. Even though it's often considered the most common diagnosis in orbital biopsies, it's still an exclusionary diagnosis that means systemic illnesses and other possible causes have to be ruled out. Though it is always an excluded clinical diagnosis, acute orbital symptoms such discomfort, exophthalmos, periorbital edema, chemosis, diplopia, and vision impairment are commonly associated with NSOI. Clinical diagnosis and management of NSOI provide a substantial difficulty. There are presently no recognized diagnostic criteria or standard treatment strategy for NSOI, and the clinical symptoms and histological features show significant variation. This guide was formulated under the auspices of the Ocular Oncology Committee of the Opthalmology Branch of the Chinese Medical Doctor Association, Opthalmology Committee of International Association of Intelligent Medicine, Opthalmology Committee of International Association of Translational Medicine making a detailed summary of the definition, classification, diagnosis and treatment of the NSOI, with a view to aiding clinicians to improve diagnostic efficiency and formulate a better treatment plan for patients.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.82160195,82460203); 江西省双千计划科技创新高端领军人才项目(No.jxsq2023201036); 江西省重大(重点)研发专项计划(No.20223BBH80014)
