[关键词]
[摘要]
外泌体在各类体液中普遍存在，且含量丰富种类多样。因其特殊的结构、功能参与了细胞间通讯、物质运输、免疫调节等生命活动。越来越多的研究发现外泌体中有诊断糖尿病视网膜病变的标志物，也是治疗糖尿病视网膜病变新的突破口，具有良好的临床应用前景。文章基于外泌体的生物学功能，探究糖尿病视网膜病变中外泌体的诊断和治疗机制，总结外泌体在糖尿病视网膜病变诊断和治疗研究中的进展，实现对糖尿病视网膜病变更有效的临床诊断和治疗。
[Key word]
[Abstract]
Exosomes are ubiquitous in all types of body fluids, exhibiting a high degree of abundance and diversity. Given their distinctive structure and function, exosomes are involved in a range of life activities, including intercellular communication, material transport, and immune regulation. An increasing number of studies have identified exosomes as a source of diagnostic markers for diabetic retinopathy. Furthermore, exosomes represent a novel avenue for therapeutic intervention, with promising clinical applications. This paper examines the diagnostic and therapeutic mechanisms of exosomes in diabetic retinopathy, reviews the advancements in exosomes-based diagnostics and therapeutics for diabetic retinopathy, and aims to enhance the precision and efficiency of clinical diagnosis and treatment of diabetic retinopathy.
[中图分类号]
[基金项目]
深圳市创新委基础研究项目(No.JCYJ20210324125614039)
