目的：探讨高血压视网膜病变(HRP)患者眼底血流相关参数与颈动脉超声血流参数的相关性。

方法：回顾性纳入2021-06/2023-06在我院收治的50例50眼(左22眼，右28眼)HRP患者为试验组，并同期纳入50名50眼(左22眼，右28眼)健康体检者为健康组。并使用Pearson相关性分析眼底血流相关参数与颈动脉超声血流参数的相关性。

结果：眼底血流相关参数与颈动脉超声血流参数及两者联合诊断HRP的AUC值分别为0.853、0.844、0.935。Pearson相关性分析显示，颈动脉收缩期峰值血流速度与中心凹无血管区(FAZ)面积、FAZ周长、非圆度指数呈负相关，与黄斑区血管密度呈正相关(均P<0.05)； 舒张末期血流速度与FAZ面积和黄斑区血管密度呈正相关(均P<0.05)； 颈内动脉阻力指数与FAZ面积呈正相关(P<0.05)。

结论：眼底血流相关参数与颈动脉超声血流参数联合诊断HRP均具有较好的应用价值。

METHODS: A total of 50 patients(22 left eyes and 28 right eyes)with HRP admitted to our hospital from June 2021 to June 2023 were retrospectively included as the experimental group, and 50 healthy physical examination subjects(22 left eyes and 28 right eyes)during the same period were included as the healthy group. Pearson correlation was used to analyze the correlation between fundus blood flow parameters and carotid artery ultrasound blood flow parameters.

RESULTS: The AUC values of fundus blood flow parameters and carotid artery ultrasound blood flow parameters and their combined diagnosis of HRP were 0.853, 0.844 and 0.935, respectively. Pearson correlation analysis showed that carotid systolic peak blood flow velocity was negatively correlated with foveal avascular zone(FAZ)area, FAZ circumference and non-circularity index, and positively correlated with macular vascular density(all P<0.05). The end-diastolic blood flow velocity was positively correlated with FAZ area and macular vascular density(all P<0.05). The internal carotid artery resistance index was positively correlated with FAZ area(P<0.05).

CONCLUSION: The combination of fundus blood flow parameters and carotid artery ultrasound blood flow parameters in the diagnosis of HRP has good application value in the diagnosis of HRP.