目的：探究强脉冲光(IPL)结合睑板腺按摩及妥布霉素地塞米松眼膏治疗伴有睑板腺功能障碍的白内障超声乳化(PHACO)术后干眼(DE)的疗效及安全性。

方法：选择2022-01/2023-12本院超声乳化术后伴有睑板腺功能障碍的DE患者100例100眼，按照治疗方法不同将其分为对照组(行睑板腺按摩+眼膏治疗)、观察组(行IPL+睑板腺按摩+眼膏治疗)各50例50眼，比较两组睑板腺分泌物状态评分、泪膜破裂时间(BUT)、临床疗效和安全性。

结果：治疗后两组睑板腺分泌物状态评分均降低，且观察组评分更低(均P<0.05)； 两组治疗后BUT均提高，且观察组BUT更高(P<0.05)； 观察组临床疗效(98%)高于对照组(84%)(P<0.05)； 观察组不良反应发生率(6%)低于对照组(20%)(P<0.05)。

结论：IPL结合睑板腺按摩及妥布霉素地塞米松眼膏能够有效提高PHACO术后DE患者的临床疗效，降低不良反应发生率，有较高的治疗安全性。

METHODS: A total of 100 cases(100 eyes)of DE patients with meibomian gland dysfunction after receiving PHACO in our hospital from January 2022 to December 2023 were selected and divided into control group(receiving meibomian gland massage + eye ointment)and observation group(receiving IPL + meibomian gland massage + eye cream treatment)according to different treatment methods, with 50 cases(50 eyes)in each group. The score of meibomian gland secretion, tear film break-up time(BUT), clinical efficacy and safety were compared between the two groups.

RESULTS: After treatment, the scores of the meibomian gland secretion status decreased in both groups, and the observation group had lower scores(all P<0.05). After treatment, the BUT increased in both groups, and the observation group had higher BUT(P<0.05). The clinical efficacy of the observation group(98%)was higher than that of the control group(84%; P<0.05). In addition, the incidence of adverse reactions in the observation group(6%)was lower than that in the control group(20%; P<0.05).

CONCLUSION: IPL combined with meibomian gland massage and tobramycin and dexamethasone ophthalmic ointment can effectively improve the clinical efficacy of DE patients after PHACO surgery, reduce adverse reactions, and have high safety.