[关键词]
[摘要]
弱视(amblyopia)是一种常见的视觉发育障碍性疾病，是儿童和成人单眼视力障碍的主要原因。光的生物调节(PBM)作为一种非侵入性、无创的治疗手段，逐渐在眼科领域受到关注。文章从光对弱视动物模型的宏观体现入手，同时结合患者弱视眼视网膜及中枢神经系统的病理变化，阐述PBM在视觉感受和处理系统的影响及机制、以及其通过多巴胺和褪黑素对视觉系统的作用，探讨其作用机制、临床应用现状以及未来发展方向，以期为弱视治疗提供新的思路和理论依据。
[Key word]
[Abstract]
Amblyopia is a common visual development disorder and is the main cause of monocular vision impairment in children and adults. Photobiomodulation(PBM), a non-invasive treatment method, has gradually gained attention in the field of ophthalmology. This paper begins with the macroscopic manifestation of light on the animal model of amblyopia. Additionally, it discusses the pathological changes of the amblyopic retina and the human eye's central nervous system, as well as the influence and mechanism of PBM on the visual perception and processing system and its chemical effect on the visual system through dopamine and melatonin. It examines its mechanism of action, current clinical application status, and future development direction in order to provide new ideas and theoretical foundation for amblyopia treatment.
[中图分类号]
[基金项目]
国家级眼科临床重点专科开放课题(No. ZKF2024050); 云南省科技厅科技计划项目(No.202201AY070001-276)
