目的：探究同轴微切口超声乳化联合人工晶状体(IOL)植入术治疗年龄相关性白内障的效果。

方法：选取2022年12月至2023年12月在本院就诊的年龄相关性白内障患者98例98眼，依据手术方式的不同分为对照组和观察组，各49例49眼。对照组接受3.0 mm标准切口超声乳化联合IOL植入术治疗，观察组接受2.2 mm同轴微切口超声乳化联合IOL植入术治疗。比较两组术前、术后各时段最佳矫正视力(BCVA)、角膜散光以及角膜内皮细胞各指标的差异，并统计患者术后并发症的发生情况，评价治疗的安全性。

结果：与术前比较，两组术后1 d，1 wk，1、3 mo的BCVA(LogMAR)均降低(P<0.05)，且观察组患者术后1 d，1 wk，1、3 mo的BVCA均优于对照组(P<0.05)。与术前比，两组术后1 d，1 wk，1 mo的角膜散光均升高(P<0.05)； 与术前比，两组术后3 mo的角膜散光无差异(P>0.05)； 术后3 mo两组角膜散光比较无差异(P>0.05)。与术前比较，两组患者术后3 mo的角膜内皮细胞密度、六角细胞比例均降低，角膜内皮细胞变异系数升高(P<0.05)，但两组术后上述指标比较无差异(P>0.05)。两组术后并发症发生率分别为8%(4/49)和4%(2/49)，两组比较无差异(P>0.05)。

结论：同轴微切口超声乳化联合IOL植入术能提高年龄相关性白内障患者的BCVA，减少对角膜散光度的影响，较为安全。

METHODS:A total of 98 patients(98 eyes)with age-related cataract in our hospital from December 2022 to December 2023 were selected. According to the different surgical methods, they were divided into control group and observation group, with 49 cases(49 eyes)in each group. The control group was treated with 3.0 mm standard incision phacoemulsification combined with IOL implantation, and the observation group was treated with 2.2 mm coaxial micro-incision phacoemulsification combined with IOL implantation. The best corrected visual acuity(BCVA), corneal astigmatism and corneal endothelial cell indexes were compared between the two groups before and after surgery. The occurrence of postoperative complications was counted to evaluate the safety of the treatment.

RESULTS: The BCVA(LogMAR)of the two groups decreased at 1 d, 1 wk, 1 and 3 mo after surgery(P<0.05), and the BVCA of the observation group was better than that of the control group at 1 d, 1 wk, 1, and 3 mo after surgery(P<0.05). Compared with pre-operation, the corneal astigmatism of the two groups increased at 1 d, 1 wk and 1 mo after operation(P<0.05), and there was no significant difference between the two groups in corneal astigmatism at 3 mo after surgery(P>0.05). There was no significant difference between the two groups in corneal astigmatism at 3 mo after operation(P>0.05). Compared with the preoperative values, the corneal endothelial cell density and hexagonal cell proportion were significantly decreased, and the coefficient of variation of corneal endothelial cells was increased in the two groups at 3 mo after surgery(P<0.05), but there was no significant difference between the two groups in the above indexes after surgery(P>0.05). The incidence of postoperative complications in the two groups was 8%(4/49)and 4%(2/49), respectively, and the difference was not statistically significant(P>0.05).

CONCLUSION: Coaxial micro-incision phacoemulsification combined with IOL implantation can improve the BCVA of age-related cataract patients, and reduce the influence of corneal astigmatism, which is relatively safe.