AIM:To search the effect of synthesis treatment for children amblyopia of different ages.·METHODS:A total of 347 eyes of 196 children were conducted the comprehensive therapy.Retinoscopy optometry was conducted after mydriasis by 10g/L Atropine on amblyopia children aged 3 to 11 years,retinoscopy optometry was conducted after mydriasis by compound tropicamide on amblyopia children aged over 11 years,and then the comprehensive amblyopia therapy was conducted to those who fitted for eyeglasses after re-examined.·RESULTS:The basic amblyopia cure rate was 70.0% by the comparison between amblyopia degree and curative effect in this group.The basic amblyopia cure rate was 75.5% by the comparison between the age of amblyopia children and curative effect.The basic amblyopia cure rate was 78.4% by the comparison between refractive status and curative effect.The basic amblyopia cure rate was 61.4% by the comparison between adherence to treatment time and curative effect.·CONCLUSION:The curative effect of the synthesis treatment has a close relationship with the amblyopia type,degree,age and adherence to treatment time.The earlier it begins,the lighter the amblyopia degree is,the longer the adherence to treatment time is,the better the curative effect would be.