·AIM:To compare the clinical effect of intraorbital implantation of bioceramic spheres and hydroxyapatite spheres after evisceration.·METHODS:Seventy-three eyes of 73 patients were included in this study.Patients were randomly assigned to A,B groups.Thirty-five eyes were included in A group and 38 eyes in B group,respectively.After evisceration,patients in A group received the bioceramic implant and patients in B group received the hydroxyapatite implant.·RESULTS:Patients were followed-up for 6-15 months.There were no complications of implant extrusion,exposure,infection,or migration for patients in both groups.All patients in both groups had a good cosmetic result after final prosthetic fitting.Prosthetic motility was good in all patients.·CONCLUSION:Bioceramic is a safe and effective material of orbital implant for correction of anophthalmos after evisceration.The bioceramic implant is an alternative to the hydroxyapatite implant.·