AIM: To study correlation between the thickness of retinal nerve fibre layer(RNFL)detected by OCT3 and visual field defect in Uygur patients with glaucoma. METHODS: Uygur patients with glaucoma 47 cases(79 eyes), Han nationality patients with glaucoma 21 cases (38 eyes), and Uygur normal people 15 cases (30 eyes) were included. The differences of OCT3 and visual field between Uygur patients and Uygur normal and between Uygur patients and Han nationality patients were compar-ed. The correlation between RNFL thickness and visual field defect was analyzed through Uygur patients. RESULTS: OCT 1 ∶00, 6 ∶00, 7 ∶00, 11 ∶00, 12 ∶00 the mean defect and pattern standard deviation in the superotemporal quadrant and visual field showed signifi-cant difference between Uygur patients and Uygur normal. Of OCT parameters, there was no significant difference between Uygur patients and Han nationality patients. The correlation in Uygur patients between OCT and visual field defect was stronger along with stage of glaucoma. CONCLUSION: OCT had better diagnostic value in glaucoma,RNFL and visual field defect is correlated.OCT can verify visual field. Such OCT offers measure target for glaucoma.