AIM: To observe the effect of treatment of retinal vein occlusion(RVO) with hexuemingmu tablet. METHODS: Sixty-four patients were treated with hexuemingmu tablet and the effect was observed. RESULTS: The cure rate was 53%, effective rate was 41%, and the total effective rate was 94%. CONCLUSION: The therapeutic effect of hexuemingmu tablet was significant and it’s a safe and convenient drug for RVO.