AIM: To analyze the clinical treatment and curative effect of secondary glaucoma to iridocorneal endothelial(ICE) syndrome. METHODS: Ten consecutive cases (12 eyes) from August 2005 to August 2009 were performed anti-glaucoma operation in our department, the visual acuity and intraocular pressure were observed after operation. The follow-up period ranged from 3- 40 months. RESULTS: All patients performed combined trabeculectomy. Eight eyes performed successfully. Three eyes performed Ahmed valve implantation, one eye performed ciliary body photocoagulation after trabeculectomy. CONCLUSION: Combined trabeculectomy and Ahmed valve implantation is an effective way to treat glaucoma secondary to ICE syndrome.