·AIM:To analyze the clinical manifestation of Alport syndrome,especially the ocular features.·METHODS:The physical,ophthalmologic and audiologic examination results of thirty two patients with Alport syndrome were analyzed retrospectively.·RESULTS:Thirty(93.7%)patients had some family history.All patients had renal disease:eighteen(56.3%)patients with chronic renal failure,four(12.5%)patients with renal insufficiency,and the other ten(31.3%)patients with hematuria.Twenty(62.5%)patients had sensorineural deafness.Thirteen(40.6%)patients had ocular deformity,five(15.6%)patients had typical ocular changes:three patients with anterior lenticonus,and two patients with macular flecks.·CONCLUSION:Ocular anomalies are not requisite for the diagnosis of Alport syndrome.But its typical ocular features should be recognized by the ophthalmologists which supports the diagnosis.·