·Retina and choroid neovascularization(NV)may induce vitreous hemorrhage,subretinal hemorrhage and tractional retinal detachment and usually result in poor vision.It is often seen in the eyes with age-related macular degeneration(AMD),diabetic retinopathy(DR),retinal vein occlusions(RVO)and retinopathy of prematurity(ROP).At present,drugs of NV mainly target the different phases of the angiogenesis and suppress its growth.We discusse the present anti-neovascular drugs which are used on clinic or under the clinicaltrial.·