·AIM:To evaluate the clinical effect of lecithin-bound iodine and fufangxueshuantong capsule in the treatment of vitreous opacities.·METHODS:Vitreous opacity patients which had different disease time were randomly divided into two groups,the lecithin-bound iodine(LBI)group and the fufangxue-shuantong capsule group.The vitreous body turbidity situation,change of eyesight were observed under the direct ophthalmoscope and slit-lamp before the treatment and 30 days,60 days after oral drug treatment.At the same time,the vitreous body turbidity grade was evaluated.·RESULTS:After 30 days’ treatment,the effective rate of fufangxueshuantong was significantly lower than that of LBI in the fresh and short-term groups(P<0.05).After 60 days’ treatment,in the old group,there was a much higher effective rate in patients who had taken fufangxueshuantong than those who had taken LBI(P<0.05).Moreover,the total effective rate in each group were significantly higher than the efficiency of the 30 days’ treatment(P<0.05).Compared with the fresh group,the total effective rates of the long-term group and old group were significantly decreased after two drugs’ treatment(P<0.01).·CONCLUSION:LBI is more effective to the fresh and short-term vitreous opacities than fufangxueshuantong capsule,and fufangxueshuantong capsule is an ideal treatment for chronic old vitreous opacities.To extend the treatment time of vitreous opacities and offer early treatment will contribute to the improvement of treatment effectiveness.·