AIM:To explore the efficacy of neovascular glaucoma treated by pan retinal photocoagulation or pan retinal cryotherapy combined with trabeculectomy. METHODS: Sixty-four patients 64 eyes with neovascular glaucoma were first treated by retinal photocoagulation or pan retinal cryotherapy and then trabeculectomy.Postoperative visual acuity, intraocular pressure,iris neovascularization,filtering bleb ,and complications of the surgery were studied.RESULTS: Follow-up visits during the period of 6 to 12 months after the treatment showed that visual acuity did not manifest improvement but mean intraocular pressure dropped from 47.89±6.74mmHg to 18.41±2.16mmHg. The intraocular pressure of 53 eyes was controlled normal,and the success rate was 73%. CONCLUSION: Trabeculectomy combined with pan retinal photocoagulation or pan retinal cryotherapy has better long-term therapeutic efficacy in treating neovascular glaucoma.