AIM:To study the effect of photodynamic therapy (PDT) on choroidal neovascularization and the research value of related medical nursing.METHODS:The results and complications of 68 eyes in 65 cases of choroidal neovascularization treated with PDT was analyzed retrospectively.RESULTS:Improvement in visual acuity more than two lines was in 31 eyes (46%), less than two lines was in 33 eyes (49%), and worse in 4 eyes (6%).No fluorescein leakage was found in 41 eyes (60%), while decreased fluorescein leakage in 22 eyes (32%), and increased fluorescein leakage in 5 eyes (8%); backache was found in 2 cases, liquid leakage and photosensitive skin reactions was not found. Satisfaction was found in all cases.CONCLUSION:The efficacy of PDT on choroidal neovascularization is reliable. Detailed explanation and intensive care is the key factor to avoid of medical dispute.