·AIM:To evaluate the efficiency of transscleral cyclophotocoagulation(TSCPC)for refractory glaucoma.·METHODS:Retrospective analysis was made in 36 eyes with refractory glaucoma treated by TSCPC with lower energy power(1.5-2.1W)and more laser spots(10-32).Intraocular pressure(IOP),visual acuity,ocular symptoms and complications were observed after TSCPC.Patients were followed up for 3 months.·RESULTS:The mean preoperative IOP was 62.89±17.36mmHg which was significantly different from the final follow-up mean IOP,21.13±7.06mmHg(P<0.05).The success rate was 83%(30/36).Postoperative visual acuity remained unchanged in 6 eyes;improved in 4 eyes.The cyclocryotherapy were performed in 6 eyes whose IOP was not controlled.The pain sense disappeared or remarkably relieved.The main complications included mild uveitis and hyphemae.Atrophy of eyeball occurred in no eye.·CONCLUSION:TSCPC is a simple,safe and effective method for eyes with refractory glaucoma.·