·AIM:To investigate the efficacy of probing of lacrimal passages combined with tobramycin+dexamethasone eye ointment injection for chronic dacryocystitis.·METHODS:A retrospective case series was studied.From 1990-05 to 2008-05 284 patients 308 eyes with chronic dacryocystitis in our hospital underwent probing of lacrimal passages(retention time:30 minutes-2 hours)combined with tobramycin+dexamethasone eye ointment injection(dosage:1-1.5mL).Once a week with six times one treatment phase.·RESULTS:Cases with cured were in 252 eyes(81.8%)and with improvement in 56 eyes(18.2%).·CONCLUSION:The probing of lacrimal passages combined with tobramycin+dexamethasone eye ointment injection is the simple,economical and practical way for chronic dacryocystitis in primary hospital.·