AIM:To evaluate the clinical curative effect of amniotic membrane grafting for ocular chemical burn and thermal burn. ·MEHTODS:We collected 24 patients 28 eyes with ocular chemical and thermal burn,which had been treated with amniotic membrane grafting in our hospital. The follow-up time ranged from 6-24 months. The posto-perative visual acuity,the condition of amniotic mem-brane transplant,renovation of cornea,healing time of corneal epithelium and complication were observed. ·RESULTS:Postoperative corrected visual acuity:visual acuity was improved in 22 eyes(79%)and was not changed in 6 eyes(21%)after amniotic membrane grafting,no visual acuity appearances declined,and there was no statistical significance between preoperative visual acuity and postoperative visual acuity. Status of amniotic membrane implant:amniotic membrane survived in 24 eyes and the survival rate was up to 86%.Conditions of cornea:8 eyes recovered to transparent; nebula emerged in 12 eyes eventually,corneal macula emerged in 5 eyes and 3 eye ended up with leukoma. Time of corneal epi-thelium healing:corneal epithelium of 28 eyes recovered entirely,22 eyes of which recovered within 3 weeks. Symblepharon condition improved in all 4 patients who suffered from preoperative atretoblepharia,including three cases completely separate. ·CONCLUTION:Amniotic membrane grafting is an effective method to deal with ocular surface burn.